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INVITED REVIEW
Year : 2016  |  Volume : 11  |  Issue : 12  |  Page : 1869-1883

The dynamics of adult neurogenesis in human hippocampus


School of Anatomical Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

Correspondence Address:
Amadi O Ihunwo
School of Anatomical Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg
South Africa
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Source of Support: This work was supported by the Consortium for Advanced Research Training in Africa (CARTA). CARTA is jointly led by the African Population and Health Research Center (APHRC) and the University of the Witwatersrand and funded by the Wellcome Trust (UK) (Grant No. 087547/Z/08/Z), the Department for International Development (DfID) under the Development Partnerships in Higher Education (DelPHE), the Carnegie Corporation of New York (Grant No. B 8606), the Ford Foundation (Grant No. 11000399), Google. Org (Grant No. 191994), Sida (Grant No. 54100029), MacArthur Foundation (Grant No. 10-95915-000-INP) and British Council., Conflict of Interest: None


DOI: 10.4103/1673-5374.195278

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The phenomenon of adult neurogenesis is now an accepted occurrence in mammals and also in humans. At least two discrete places house stem cells for generation of neurons in adult brain. These are olfactory system and the hippocampus. In animals, newly generated neurons have been directly or indirectly demonstrated to generate a significant amount of new neurons to have a functional role. However, the data in humans on the extent of this process is still scanty and such as difficult to comprehend its functional role in humans. This paper explores the available data on as extent of adult hippocampal neurogenesis in humans and makes comparison to animal data.


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