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  Indian J Med Microbiol
 

Figure 5: Inhibition of human beta-site amyloid precursor protein cleaving enzyme 1, by S. pilchardus chondroitin sulfate A (blue) or porcine mucosal heparin (black) as determined by Förster resonance energy transfer. Porcine mucosal heparin IC50 = 2.6 µg/mL with an R2 of 0.97; S. pilchardus chondroitin sulfate A extract IC50 = 4.8 µg/mL with an R2 of 0.93. GAG: Glycosaminoglycan; IC50: half maximal inhibitory concentration.

Figure 5: Inhibition of human beta-site amyloid precursor protein cleaving enzyme 1, by <i>S. pilchardus</i> chondroitin sulfate A (blue) or porcine mucosal heparin (black) as determined by Förster resonance energy transfer. Porcine mucosal heparin IC<sub>50</sub> = 2.6 µg/mL with an R<sup>2</sup> of 0.97; <i>S. pilchardus</i> chondroitin sulfate A extract IC<sub>50</sub> = 4.8 µg/mL with an R<sup>2</sup> of 0.93. GAG: Glycosaminoglycan; IC<sub>50</sub>: half maximal inhibitory concentration.