Figure 1: Illustration of contused spinal cord receiving local drug delivery. Portion of spinal cord is removed to allow for visualization of cord interior. (A) Drug delivered via intrathecal catheterization or (B) small drug carriers delivered via intrathecal injection are carried away by circulating CSF, compromising local delivery. (C) Intrathecal implantation of drug-loaded hydrogel results in far more localized drug delivery to the spinal cord. Drug is shown in green. CSF: Cerebrospinal fluid.