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  Indian J Med Microbiol
 

Figure 1: The origin and biology of microglia. Microglia originate from the yolk sac during embryogenesis and from bone marrow during repopulation. They act as an immunological surveillant in steady states. ARG1: Arginase 1; CNS: central nervous system; CD200R1: CD200 receptor 1; CX3CR1: CX3C chemokine receptor 1; CXCR2: C-X-C motif chemokine receptor 2; IL: interleukin; iNOS: inducible nitric oxide synthase; MARCO: macrophage receptor with collagenous structure; MHCII: major histocompatibility complex II; PPAR: peroxisome proliferator-activated receptor; TGF-β: transforming growth factor-β; TNF-α: tumor necrosis factor-α.

Figure 1: The origin and biology of microglia.
Microglia originate from the yolk sac during embryogenesis and from bone marrow during repopulation. They act as an immunological surveillant in steady states. ARG1: Arginase 1; CNS: central nervous system; CD200R1: CD200 receptor 1; CX3CR1: CX3C chemokine receptor 1; CXCR2: C-X-C motif chemokine receptor 2; IL: interleukin; iNOS: inducible nitric oxide synthase; MARCO: macrophage receptor with collagenous structure; MHCII: major histocompatibility complex II; PPAR: peroxisome proliferator-activated receptor; TGF-β: transforming growth factor-β; TNF-α: tumor necrosis factor-α.