Figure 5: Neurological function, brain water content, and blood-brain barrier leakage after PF delivery post SAH (Experiment IV). (A, B) SAH grading scores. (B, C) Modified Garcia scores and beam balance test results. (D, E) Brain water content at 24 and 72 hours after SAH. (F) Evans blue leakage at 24 hours. Data are expressed as the mean ± SD (n = 6; one-way analysis of variance and Tukey's post hoc test).*P < 0.05, vs. sham group; #P < 0.05, vs. SAH + vehicle group. MAP4K4: Sterile-20-like mitogen-activated protein kinase kinase kinase kinase 4; PF: PF-06260933; SAH: subarachnoid hemorrhage.