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  Indian J Med Microbiol
 

Figure 1: Lesion volume and midline shift explain most of the MRI data variability at 24 hours and 12 weeks post-TBI. Representative T2-weighted Fast Spin Echo images 24 hours (A) and 12 weeks (B) post-TBI images show distinct brain lesions. At 24 hours post-TBI, the midline shifted away from the ipsilateral hemisphere (C, red line) at the level of the septum pellucidum (C, yellow line), while at 12 weeks post-TBI the midline shifted toward the ipsilateral hemisphere (D, blue line). The scree plot of the five PCs at 24 hours post-TBI using covariance criteria showed that PC1 and PC2 explained most of the variability (E). The biplot of PC1 against PC2 of indicated that lesion volume and midline shift is dominant in explaining most of the variability at 24 hours post-TBI (F). The scree plot of the five PCs at 12 weeks post-TBI using covariance criteria showed that PC1 and PC2 explained most of the variability (G). The biplot of PC1 against PC2 indicated that lesion volume and midline shift is dominant in explaining most of the variability at 12 weeks post-TBI (H). MRI: Magnetic resonance imaging; PC: principal component; TBI: traumatic brain injury.

Figure 1: Lesion volume and midline shift explain most of the MRI data variability at 24 hours and 12 weeks post-TBI. 
Representative T2-weighted Fast Spin Echo images 24 hours (A) and 12 weeks (B) post-TBI images show distinct brain lesions. At 24 hours post-TBI, the midline shifted away from the ipsilateral hemisphere (C, red line) at the level of the septum pellucidum (C, yellow line), while at 12 weeks post-TBI the midline shifted toward the ipsilateral hemisphere (D, blue line). The scree plot of the five PCs at 24 hours post-TBI using covariance criteria showed that PC1 and PC2 explained most of the variability (E). The biplot of PC1 against PC2 of indicated that lesion volume and midline shift is dominant in explaining most of the variability at 24 hours post-TBI (F). The scree plot of the five PCs at 12 weeks post-TBI using covariance criteria showed that PC1 and PC2 explained most of the variability (G). The biplot of PC1 against PC2 indicated that lesion volume and midline shift is dominant in explaining most of the variability at 12 weeks post-TBI (H). MRI: Magnetic resonance imaging; PC: principal component; TBI: traumatic brain injury.