Figure 1: Effects of H2S on MPTP-induced PD mouse model. (A) Schematic of protocol for establishing the MPTP mouse model of PD. (B, C) Cresyl violet staining and quantitative data for Nissl-positive neurons in the SNc (original magnification 10×, scale bar: 40 μm). Red circles represent the SNc brain region. Data are expressed as mean ± SEM (n = 6). **P < 0.01, ***P < 0.001, vs. saline group; ###P < 0.001, vs. MPTP group (one-way analysis of variance followed by Tukey’s post hoc test. All samples were detected repeatedly in three independent experiments. H2S: Hydrogen sulfide; i.p.: intraperitoneal injection; MPTP: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NaHS: sodium hydrosulfide, a donor of H2S; PD: Parkinson’s disease; s.c: subcutaneously; SNc: substantia nigra pars compacta.