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  Indian J Med Microbiol
 

Figure 1: Effects of H2S on MPTP-induced PD mouse model. (A) Schematic of protocol for establishing the MPTP mouse model of PD. (B, C) Cresyl violet staining and quantitative data for Nissl-positive neurons in the SNc (original magnification 10×, scale bar: 40 μm). Red circles represent the SNc brain region. Data are expressed as mean ± SEM (n = 6). **P < 0.01, ***P < 0.001, vs. saline group; ###P < 0.001, vs. MPTP group (one-way analysis of variance followed by Tukey’s post hoc test. All samples were detected repeatedly in three independent experiments. H2S: Hydrogen sulfide; i.p.: intraperitoneal injection; MPTP: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NaHS: sodium hydrosulfide, a donor of H2S; PD: Parkinson’s disease; s.c: subcutaneously; SNc: substantia nigra pars compacta.

Figure 1: Effects of H<sub>2</sub>S on MPTP-induced PD mouse model.
(A) Schematic of protocol for establishing the MPTP mouse model of PD. (B, C) Cresyl violet staining and quantitative data for Nissl-positive neurons in the SNc (original magnification 10×, scale bar: 40 μm). Red circles represent the SNc brain region. Data are expressed as mean ± SEM (<i>n</i> = 6). **<i>P</i> < 0.01, ***<i>P</i> < 0.001, <i>vs</i>. saline group; ###<i>P</i> < 0.001, <i>vs</i>. MPTP group (one-way analysis of variance followed by Tukey’s <i>post hoc</i> test. All samples were detected repeatedly in three independent experiments. H<sub>2</sub>S: Hydrogen sulfide; i.p.: intraperitoneal injection; MPTP: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NaHS: sodium hydrosulfide, a donor of H<sub>2</sub>S; PD: Parkinson’s disease; s.c: subcutaneously; SNc: substantia nigra pars compacta.