Figure 1: ABNs may influence mGC theta phase-locked activity during memory consolidation in REM sleep. (A) Theta phase-locked ABNs and non-phase-locked ABNs in the hippocampus. (B) Theta phase-locked activity stabilizes ABN spines, whereas non-phase-locked activity eliminates ABN spines. (C) Phase-locked ABN activity may inhibit mGC activity in a theta phase-specific manner, thereby coordinating the activity of mGCs at the reciprocal phase. (D) Phase-locked mGC activity may induce modifications in synaptic strength that establish a memory trace. ABN: Adult-born neurons; mGC: mature granular cell.