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  Indian J Med Microbiol
 

Figure 3: Antinociceptive effects of PPX in reserpinized mice. Effects of therapeutic treatment with PPX (0.1, 1 and 5 mg/kg, intraperitoneally) were measured through the tail-flick test on the 3rd, 4th, 9th, and 14th days after reserpine administration (0.25 mg/kg, subcutaneously). Each column represents the mean ± SEM of nine to eleven mice/group and are representative of two independent experiments (ntotal = 18–22 mice/group). *P < 0.05, **P < 0.01, vs. reserpine group; #P < 0.05, ##P < 0.001, vs. vehicle group (one-way analysis of variance followed by Newman-Keuls post hoc test). PPX: Pramipexole.

Figure 3: Antinociceptive effects of PPX in reserpinized mice.
Effects of therapeutic treatment with PPX (0.1, 1 and 5 mg/kg, intraperitoneally) were measured through the tail-flick test on the 3<sup>rd</sup>, 4<sup>th</sup>, 9<sup>th</sup>, and 14<sup>th</sup> days after reserpine administration (0.25 mg/kg, subcutaneously). Each column represents the mean ± SEM of nine to eleven mice/group and are representative of two independent experiments (<i>n</i><sub>total</sub> = 18–22 mice/group). *<i>P</i> < 0.05, **<i>P</i> < 0.01, <i>vs</i>. reserpine group; #<i>P</i> < 0.05, ##<i>P</i> < 0.001, <i>vs</i>. vehicle group (one-way analysis of variance followed by Newman-Keuls <i>post hoc</i> test). PPX: Pramipexole.